Patterns of linkage disequilibrium at PARK16 may explain variances in genetic association studies.
Identifieur interne : 000123 ( Main/Exploration ); précédent : 000122; suivant : 000124Patterns of linkage disequilibrium at PARK16 may explain variances in genetic association studies.
Auteurs : Huihua Li ; Yik-Ying Teo [Singapour] ; Eng-King TanSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2015.
Abstract
Reproducing genomewide association studies findings in different populations is challenging, because the reproducibility fundamentally relies on the similar patterns of linkage disequilibrium between the unknown causal variants and the genotyped single-nucleotide polymorphisms (SNPs).
DOI: 10.1002/mds.26176
PubMed: 25758099
Affiliations:
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